Dr. Pimple Popper treated a woman with a painful 'horn' growing on the back of her head

But the seasons' sixth episode, which aired Thursday night, featured something entirely new: A woman with a hard "horn" growing from the skin on the back of her head.

Here's a closer look at the episode.

Lisa had a painful 'horn' growing out of her scalp

Lisa, 42, explained in an interview segment that a hardened horn started to grow from the back of her head about a year prior.

"It grows every day, it gets bigger, it's painful at times," she said in the episode. "I don't want anybody to see it so I wear my hair up...the growth makes me feel gross."

Lisa added that, even though she's engaged, she's put off setting a wedding date because of the horn.

"Usually when you get married, you're standing in front of everybody with your back to them," she said. "That's the first thing I think they're going to see."

But her concerns were more than just cosmetic.

"My worst fear is that it is cancer," Lisa said. "[It's] probably time I should get it checked. I have not been to a doctor about it. I don't have insurance, so that's the main reason. I don't really like doctors, either. But it's not going to go away on its own."

Lee said it may have been a sign of skin cancer

In an exam room at Lee's office, Lisa gave more detail about the horn's genesis: She had a cyst on her scalp that "broke" open, and then she squeezed it.

"It came to a point when I couldn't squeeze it anymore, and then this started growing," she said.

After a brief exam of, Lee dubbed the growth a "cutaneous horn."

Cutaneous horns are growths made of a compacted protein called keratin, according to a 2004 paper on the growths published in the World Journal of Surgical Oncology. They're shaped (as you might expect) a lot like animal horns. These "horns" can grow outward from a variety of different skin issues, from benign moles and warts to malignant problems like skin cancer. One older study looking at 643 cases of cutaneous horns found that just over 60% were caused by something benign .

In the episode, Lee said she has seen cutaneous horns before. In fact, she even featured a patient with such a growth in an August 2017 YouTube video .

But she added that Lisa's horn was the largest she'd ever encountered.

She also expressed concern that its root cause may have been skin cancer.

"I'm not exactly sure what it is... [it] sounds like it could be a pilar cyst and it has grown out of control," Lee told Lisa in the episode. "This is the angriest pilar cyst I've ever seen if thats the case. Usually, when we see a cutaneous horn, we do think of other things that might be a little bit more concerning. [It] can happen with types of skin cancers."

She removed it in one piece and testing revealed it was benign

In a quick procedure, Lee numbed the area around Lisa's growth and slowly pulled it off in one piece. After removing some skin to send to a lab for testing, Lee stitched up the area. She even grabbed a metal tray and knocked the horn against to demonstrate how hardened it was.

Later, Lisa returned to Lee's office for a follow-up appointment and for test results.

Luckily, the news was good: The horn had arisen from a cyst, not from skin cancer.

"The dermatopathologist read your slide and they say it's an inflamed follicular cyst," Lee told Lisa. "There's no risk of cancer. I dont think it's ever coming back."

When I get home and I see my daughter, I'm going to tell her that she has to put up with me for many more years to come," Lisa said that the close o the episode.

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